To view other topics, please sign in or purchase a subscription. Zithromax is a macrolide antibacterial drug indicated for mild to moderate infections caused by designated, susceptible bacteria. In the largest trial so far involving coadministration of regimens based on ivermectin and azithromycin, the combination was safe and feasible in a population of more than 26 000 people. With all the information youve come to expect from our print guides, greatly expanded digitalonly content, and interactive calculators, algorithms, and tables, the web edition is an indispensable resource for todays healthcare. This product information is intended only for residents of the united states. Sep 24, 2009 drug drug interaction study of colchicine and azithromycin the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Safely throw away any medicine that is out of date or no longer needed. Azithromycin is a bacteriostatic drug acts by inhibiting protein synthesis. For information regarding the use of zithromax azithromycin for oral suspension in the treatment of pediatric patients, see indications and usage 1 and dosage and administration 2 of the prescribing information for zithromax azithromycin for oral suspension 100 mg5 ml and 200 mg5 ml bottles. Fda warns about increased risk of cancer relapse with long. So you can take azithromycin tablets or suspension without regard to meals. Azithromycin is a pregnancy category b1 drug and is considered safe to. Reducing local azithromycin did for treatment is entered to physical, yersinia pestis, mid this potential to to you and maybe waiting the many out of your health care, azithromycin is feasible and pediatric for the relationship of odor.
Refer to the fda label and indications section of this drug entry for detailed information. Azithromycin reversibly binds to the bacterial ribosome and inhibits protein synthesis. Zithromax azithromycin dihydrate dosage and administration. The typical liver injury caused by azithromycin resembles that described with other macrolides and is a selflimited, cholestatic hepatitis, arising within 1 to 3 weeks of starting treatment case 1. Azithromycin oral tablet zithromax is a prescription drug thats used to treat infections caused by bacteria. Learn vocabulary, terms, and more with flashcards, games, and other study tools.
Injection powder, lyophilized, for solution several fdaapproved drug labels may be available for azithromycin. If you wish to start a new drug or natural product, please consult with your pharmacist before doing so. This medication is usually safe when taken with most other medications. Azithromycin vomits the least qt incubation, and conjunctival old concentration deaths. Find patient medical information for azithromycin oral on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Azithromycin extendedrelease zmax for sinusitis and pneumonia. Azithromycin comes as a tablet, an extendedrelease longacting suspension liquid, and a suspension liquid to take by mouth. Mar 27, 2020 azithromycin oral tablet zithromax is a prescription drug thats used to treat infections caused by bacteria. In 2017, azithromycin was the second most prescribed antibiotic for outpatients in the united states. The tablets should be taken with a full glass of water. Azithromycin is a macrolide antibiotic used to treat a wide range of clinical conditions, including bacterial conjunctivitis, upper respiratory tract bacterial infections, some patients with bacterial communityacquired pneumonia cap, disseminated mycobacterium avium complex mac, pertussis, chlamydia, gonococcal stds, and cat scratch disease.
Food and drug administration fda is warning the public that azithromycin zithromax or zmax can cause abnormal changes in the electrical activity of the heart that may lead to a. Feasibility and safety of mass drug coadministration with. For example, when used to prevent mac the usual dose of azithromycin is. Zithromax azithromycin dihydrate fdaapproved patient. Concentrationtime profiles of azithromycin in plasma, muscle, subcutis, and wbc during i. Azithromycin oral interactions with other medication. Inclusion or absence of a drug label on the aidsinfo site does not imply endorsement or lack thereof by aidsinfo. Read this patient information leaflet before you start taking zithromax and each time you get a refill. Azithromycin 3 day dose pack, azithromycin 5 day dose pack, zithromax, zithromax iv, zithromax tripak, zithromax zpak generic name. Azithromycin is an antibiotic used for the treatment of a number of bacterial infections. Azithromycin alphapharm azithromycin drug medicine. Zithromax azithromycin is a macrolide antibacterial drug indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below. Food and drug administration fda for the treatment of certain bacterial infections, such as.
Nursing central is an awardwinning, complete mobile solution for nurses and students. Zithromax may also be used for purposes not listed in this medication guide. Product information for zithromax, biaxin, physicians desk reference, 1995. Zithromax azithromycin 250 mg and 500 mg tablets and oral. Until further data are developed regarding drug interactions when digoxin, colchicine or phenytoin are used with azithromycin careful monitoring of patients is advised. Do not take more or less of it or take it more often than prescribed by your clinician. Keep zithromax and all medicines out of the reach of children. Coadministration of mass drug administration based on these two drugs opens up new potential for the control of neglected tropical diseases. Acute bacterial exacerbations of chronic bronchitis in adults acute bacterial sinusitis in adults uncomplicated skin and skin structure infections in adults urethritis and cervicitis in adults genital ulcer disease in men. Using lumefrantine and azithromycin can increase the risk of an.
This leaflet answers some common questions about azithromycin alphapharm. It can also be used for a number of sexually transmitted infections, including chlamydia and gonorrhea infections. Various bacterial respiratory diseases, including communityacquired pneumonia, acute sinus and ear infections, and acute worsening of chronic bronchitis. Rifampicin is effective in areas where doxycycline resistance is present. Azithromycin 250mg and 500mg filmcoated tablets package leaflet. Drugs that may influence the effect of azithromycin include aluminum and magnesiumcontaining antacids and drugs ie. Along with other medications, it may also be used for malaria. Azithromycin is used to treat many different types of infections caused by bacteria, including infections of the lungs, sinus, throat, tonsils, skin, urinary tract, cervix, or genitals. Azithromycin and other antibacterial drugs, gd azithromycin should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. Hypersensitivity to azithromycin, erythromycin, or other ma. Reducing local azithromycin did for treatment is entered to physical, yersinia pestis, mid this potential to to you and maybe waiting the many out of your health care, azithromycin is. Azithromycin may also be used for purposes not listed in this medication guide. Zithromax azithromycin is an antibiotic that fights bacteria.
The tablets and suspension zithromax are usually taken with or without food once a day for 15 days. To reduce the development of drug resistant bacteria and maintain the effectiveness of zithromax azithromycin and other antibacterial drugs, zithromax azithromycin should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. Because azithromycin has become so commonly used, it has also become one of the more common causes of drug induced liver injury. Zithromax azithromycin side effects, images, uses, dosage. Antibiotic drugs, information, description on azithromycin. Zithromax azithromycin dihydrate pfizer medical information. Capitals indicate life threatening, underlines indicate most frequent. Listing a study does not mean it has been evaluated by the u.
To reduce the development of drug resistant bacteria and maintain the effectiveness of zmax azithromycin and other antibacterial drugs, zmax azithromycin should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. This information does not take the place of talking to your healthcare provider about your medical condition or your treatment. Depending on the type of infection you have, the dose of azithromycin will vary. Zithromax azithromycin tablets and azithromycin for oral suspension to reduce the development of drug resistant bacteria and maintain the effectiveness of zithromax azithromycin and other antibacterial drugs, zithromax azithromycin should be used only to treat or prevent infections that are proven or strongly suspected to be. Azithromycin interferes with transpeptidation and translocation thus there is inhibition of protein synthesis and hence inhibition of cell growth. Store zithromax oral suspension at 41f to 86f 5c to 30c. Aidsinfo provides the following drug label solely as an example of the labels available for azithromycin. Drugdrug interaction study of colchicine and azithromycin. Zithromax is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. Do not use zithromax for a condition for which it was not prescribed. However, drug interactions have been observed with other macrolide products. Azithromycin fda label aidsinfo information on hiv. Zithromax azithromycin 250 mg and 500 mg tablets, for oral use. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy.
No specific drug interaction studies have been performed to evaluate potential drug drug interaction. Recommended dosages and durations of therapy in adult and pediatric patient populations vary in these indications. However, inform your doctor and pharmacist of all prescribed and non prescribed drugs. Jan 03, 2019 azithromycin may also be used for purposes not listed in this medication guide. Capitals indicate lifethreatening, underlines indicate most frequent. Azithromycin is rapidly absorbed from the gastrointestinal gi tract after oral administration. Pending revision, the material in this section should be considered in light of more recently available information in the medwatch notification at the beginning of this monograph. Azithromycininduced liver injury american journal of. May 15, 2010 concentrations within the liver exceed the serum concentrations by 25 to 200fold due to the drugs long elimination halflife 68 hours, extensive drug uptake by the liver, and subsequent release of azithromycin from tissues. Azithromycin reversibly binds to the 50s ribosomal subunit of the 70s ribosome of sensitive microorganisms, thereby inhibiting the translocation step of protein synthesis, wherein a newly synthesized peptidyl trna molecule moves from the. What is the most important information i should know about azithromycin. Zithromax azithromycin for injection is a macrolide antibacterial drug indicated for the treatment of patients with infections caused by susceptible strains of the designated microorganisms in the conditions listed below.
It binds reversibly to 50s ribosomal subunits of sensitive microorganism. Unlike clarithromycin, azithromycin does not interact significantly with cytochrome p450 3a4. You should not use azithromycin if you have ever had jaundice or liver problems when you have previously taken this medicine. You should not use azithromycin if you are allergic to it, or if. Take azithromycin until you finish the prescription, even if you feel better. Zithromax 500 mg white to off white, unscored, modified capsuleshaped film coated tablets marked ztm 500 on one side and pfizer on the other. Azithromycin is an antibiotic that fights bacteria. It is distinguished from other macrolides by its rapid and extensive. Zithromax azithromycin tablets and azithromycin for oral suspension contain. The absolute oral bioavailability of azithromycin is reported to be approximately 34% to 52% with single doses of 500 mg to 1. Blood, tissue, and intracellular concentrations of. Azithromycin, tablet, film coated, 600 mg1, oral, greenstone llc.
Azithromycin should not be taken by people who cannot tolerate oral medications. Highlights of prescribing information days 2 through 5. If you are taking azithromycin capsules, you should take the medication on empty stomach. Zithromax azithromycin dihydrate drug interactions. Azithromycin may also be used to treat other types of infections such as bacterial pneumonia, toxoplasmosis, and sexually transmitted diseases ie.
Dec 06, 2018 azithromycin is an antibacterial prescription medicine approved by the u. It does not take the place of talking to your doctor or pharmacist. Our web edition integrates antimicrobial therapy, hivaids therapy, and hepatitis therapy into a single searchable web site for maximum coverage and ease of use. Drug interaction studies were performed with oral azithromycin and other drugs likely to be coadministered. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is. If you have any further questions, ask your doctor or pharmacist. Quinolones have shown some degree of efficacy but the. General information about the safe and effective use of zithromax.
Find information on azithromycin zithromax, zmax in daviss drug guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Sandoz azithromycin azithromycin monohydrate for oral. Azithromycin brand names first online drug index of. Azithromycin is an azalide, derived from erythromycin, and a member of a subclass of macrolide antibiotics with bacteriocidal and bacteriostatic activities. Look up information on diseases, tests, and procedures. Zithromax azithromycin is a macrolide antibacterial drug indicated for the treatment of patients with mild to moderate infections. Zithromax for oral suspension can be taken with or without food. Medicines are sometimes prescribed for purposes other than those listed in the patient information leaflet. Stopping azithromycin too soon may cause bacteria to become resistant to antibiotics. Azithromycin is an antibiotic that fights bacteria azithromycin is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, eye infections, and sexually transmitted diseases.
In 2010, azithromycin was the most prescribed antibiotic for outpatients in the us, whereas in sweden, where outpatient antibiotic use is a third as prevalent, macrolides are only on 3% of prescriptions. Pocket manual of drug use in clinical medicine, 6th ed, improved therapeutics, indianapolis 1994. Zithromax fda prescribing information, side effects and uses. In the light of this latest data, healthcare professionals. Azithromycin is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, eye infections, and sexually transmitted diseases.